Miles between Des Moines, IA and Kirksville, MO

There are
151 mi
from Des Moines, IA to Kirksville, MO

That's the driving distance. It would take 3 hours 7 mins to go from Des Moines, Iowa to Kirksville, Missouri.

The flight distance (direct flight from Des Moines, IA to Kirksville, MO) is 110.92 mi.

151 mi = 243.04 kms