There are
774 mi
from Denton, TX to Owensboro, KY
That's the driving distance. It would take 13 hours 55 mins to go from Denton, Texas to Owensboro, Kentucky.
The flight distance (direct flight from Denton, TX to Owensboro, KY) is 645.20 mi.
774 mi = 1,245.58 kms