There are
970 mi
from Dayton, OH to Opelousas, LA
That's the driving distance. It would take 17 hours 58 mins to go from Dayton, Ohio to Opelousas, Louisiana.
The flight distance (direct flight from Dayton, OH to Opelousas, LA) is 777.06 mi.
970 mi = 1,560.38 kms