There are
2,199 mi
from Daly City, CA to Sikeston, MO
That's the driving distance. It would take 1 day 14 hours to go from Daly City, California to Sikeston, Missouri.
The flight distance (direct flight from Daly City, CA to Sikeston, MO) is 1,799.24 mi.
2,199 mi = 3.22 kms