Miles between Columbus, IN and Kirksville, MO

There are
449 mi
from Columbus, IN to Kirksville, MO

That's the driving distance. It would take 8 hours 21 mins to go from Columbus, Indiana to Kirksville, Missouri.

The flight distance (direct flight from Columbus, IN to Kirksville, MO) is 360.66 mi.

449 mi = 722.88 kms