Miles between Columbia, SC and St Marys, PA

There are
645 mi
from Columbia, SC to St Marys, PA

That's the driving distance. It would take 12 hours 37 mins to go from Columbia, South Carolina to St Marys, Pennsylvania.

The flight distance (direct flight from Columbia, SC to St Marys, PA) is 531.51 mi.

645 mi = 1,038.81 kms