Miles between Columbia, SC and Port St Lucie, FL

There are
525 mi
from Columbia, SC to Port St Lucie, FL

That's the driving distance. It would take 9 hours 36 mins to go from Columbia, South Carolina to Port St Lucie, Florida.

The flight distance (direct flight from Columbia, SC to Port St Lucie, FL) is 466.40 mi.

525 mi = 845.43 kms