Miles between Columbia, SC and Picayune, MS

There are
651 mi
from Columbia, SC to Picayune, MS

That's the driving distance. It would take 11 hours 52 mins to go from Columbia, South Carolina to Picayune, Mississippi.

The flight distance (direct flight from Columbia, SC to Picayune, MS) is 558.97 mi.

651 mi = 1,047.12 kms