Miles between Columbia, SC and Knoxville, TN

There are
263 mi
from Columbia, SC to Knoxville, TN

That's the driving distance. It would take 5 hours 8 mins to go from Columbia, South Carolina to Knoxville, Tennessee.

The flight distance (direct flight from Columbia, SC to Knoxville, TN) is 212.18 mi.

263 mi = 423.80 kms