Miles between Columbia, MO and Sikeston, MO

There are
255 mi
from Columbia, MO to Sikeston, MO

That's the driving distance. It would take 4 hours 53 mins to go from Columbia, Missouri to Sikeston, Missouri.

The flight distance (direct flight from Columbia, MO to Sikeston, MO) is 207.26 mi.

255 mi = 411.01 kms