There are
1,894 mi
from Columbia, MO to San Luis Obispo, CA
That's the driving distance. It would take 1 day 9 hours to go from Columbia, Missouri to San Luis Obispo, California.
The flight distance (direct flight from Columbia, MO to San Luis Obispo, CA) is 1,574.56 mi.
1,894 mi = 1.61 kms