There are
1,332 mi
from Columbia, MO to Newburyport, MA
That's the driving distance. It would take 1 day 1 hour to go from Columbia, Missouri to Newburyport, Massachusetts.
The flight distance (direct flight from Columbia, MO to Newburyport, MA) is 1,148.76 mi.
1,332 mi = 1.61 kms