Miles between Columbia, MO and Lyons, IL

There are
387 mi
from Columbia, MO to Lyons, IL

That's the driving distance. It would take 7 hours 22 mins to go from Columbia, Missouri to Lyons, Illinois.

The flight distance (direct flight from Columbia, MO to Lyons, IL) is 309.09 mi.

387 mi = 622.90 kms