Miles between Columbia, MO and Lisle, IL

There are
381 mi
from Columbia, MO to Lisle, IL

That's the driving distance. It would take 7 hours 14 mins to go from Columbia, Missouri to Lisle, Illinois.

The flight distance (direct flight from Columbia, MO to Lisle, IL) is 298.29 mi.

381 mi = 613.95 kms