There are
663 mi
from Columbia, MO to Cuyahoga Falls, OH
That's the driving distance. It would take 12 hours 36 mins to go from Columbia, Missouri to Cuyahoga Falls, Ohio.
The flight distance (direct flight from Columbia, MO to Cuyahoga Falls, OH) is 592.92 mi.
663 mi = 1,067.35 kms