There are
1,805 mi
from Clayton, MO to Temecula, CA
That's the driving distance. It would take 1 day 7 hours to go from Clayton, Missouri to Temecula, California.
The flight distance (direct flight from Clayton, MO to Temecula, CA) is 1,533.83 mi.
1,805 mi = 2,905.05 kms