There are
1,191 mi
from Clayton, MO to Pompano Beach, FL
That's the driving distance. It would take 21 hours 47 mins to go from Clayton, Missouri to Pompano Beach, Florida.
The flight distance (direct flight from Clayton, MO to Pompano Beach, FL) is 1,041.60 mi.
1,191 mi = 1,915.92 kms