Miles between Clayton, MO and Lyons, IL

There are
292 mi
from Clayton, MO to Lyons, IL

That's the driving distance. It would take 5 hours 30 mins to go from Clayton, Missouri to Lyons, Illinois.

The flight distance (direct flight from Clayton, MO to Lyons, IL) is 255.83 mi.

292 mi = 469.88 kms