There are
2,047 mi
from Clayton, MO to Larkspur, CA
That's the driving distance. It would take 1 day 11 hours to go from Clayton, Missouri to Larkspur, California.
The flight distance (direct flight from Clayton, MO to Larkspur, CA) is 1,738.53 mi.
2,047 mi = 3,294.85 kms