Miles between Clayton, MO and Effingham, IL

There are
108 mi
from Clayton, MO to Effingham, IL

That's the driving distance. It would take 2 hours 5 mins to go from Clayton, Missouri to Effingham, Illinois.

The flight distance (direct flight from Clayton, MO to Effingham, IL) is 101.27 mi.

108 mi = 174.28 kms