There are
878 mi
from Clarksville, TN to Sioux Falls, SD
That's the driving distance. It would take 16 hours 13 mins to go from Clarksville, Tennessee to Sioux Falls, South Dakota.
The flight distance (direct flight from Clarksville, TN to Sioux Falls, SD) is 691.55 mi.
878 mi = 1,412.21 kms