There are
285 mi
from Clarksville, TN to Shelbyville, IN
That's the driving distance. It would take 5 hours 34 mins to go from Clarksville, Tennessee to Shelbyville, Indiana.
The flight distance (direct flight from Clarksville, TN to Shelbyville, IN) is 223.92 mi.
285 mi = 458.45 kms