There are
234 mi
from Clarksville, TN to Seymour, IN
That's the driving distance. It would take 4 hours 38 mins to go from Clarksville, Tennessee to Seymour, Indiana.
The flight distance (direct flight from Clarksville, TN to Seymour, IN) is 186.05 mi.
234 mi = 376.71 kms