There are
485 mi
from Clarksville, TN to Sandusky, OH
That's the driving distance. It would take 9 hours 59 mins to go from Clarksville, Tennessee to Sandusky, Ohio.
The flight distance (direct flight from Clarksville, TN to Sandusky, OH) is 421.65 mi.
485 mi = 780.08 kms