There are
2,292 mi
from Clarksville, TN to San Mateo, CA
That's the driving distance. It would take 1 day 16 hours to go from Clarksville, Tennessee to San Mateo, California.
The flight distance (direct flight from Clarksville, TN to San Mateo, CA) is 1,918.44 mi.
2,292 mi = 3.22 kms