There are
425 mi
from Clarksville, TN to Mishawaka, IN
That's the driving distance. It would take 8 hours 22 mins to go from Clarksville, Tennessee to Mishawaka, Indiana.
The flight distance (direct flight from Clarksville, TN to Mishawaka, IN) is 360.39 mi.
425 mi = 683.68 kms