There are
1,780 mi
from Clarksville, TN to Mesquite, NV
That's the driving distance. It would take 1 day 7 hours to go from Clarksville, Tennessee to Mesquite, Nevada.
The flight distance (direct flight from Clarksville, TN to Mesquite, NV) is 1,475.42 mi.
1,780 mi = 1.61 kms