There are
183 mi
from Clarksville, TN to Jeffersonville, IN
That's the driving distance. It would take 3 hours 41 mins to go from Clarksville, Tennessee to Jeffersonville, Indiana.
The flight distance (direct flight from Clarksville, TN to Jeffersonville, IN) is 150.03 mi.
183 mi = 293.83 kms