There are
181 mi
from Clarksville, TN to Jeffersontown, KY
That's the driving distance. It would take 3 hours 40 mins to go from Clarksville, Tennessee to Jeffersontown, Kentucky.
The flight distance (direct flight from Clarksville, TN to Jeffersontown, KY) is 151.46 mi.
181 mi = 291.77 kms