There are
362 mi
from Clarksville, TN to Chillicothe, OH
That's the driving distance. It would take 7 hours 22 mins to go from Clarksville, Tennessee to Chillicothe, Ohio.
The flight distance (direct flight from Clarksville, TN to Chillicothe, OH) is 307.20 mi.
362 mi = 582.50 kms