Miles between Chicago, IL and Cape Girardeau, MO

There are
372 mi
from Chicago, IL to Cape Girardeau, MO

That's the driving distance. It would take 6 hours 58 mins to go from Chicago, Illinois to Cape Girardeau, Missouri.

The flight distance (direct flight from Chicago, IL to Cape Girardeau, MO) is 331.50 mi.

372 mi = 598.37 kms