There are
1,697 mi
from Cheyenne, WY to Middletown, DE
That's the driving distance. It would take 1 day 6 hours to go from Cheyenne, Wyoming to Middletown, Delaware.
The flight distance (direct flight from Cheyenne, WY to Middletown, DE) is 1,531.04 mi.
1,697 mi = 2,731.45 kms