There are
279 mi
from Chattanooga, TN to Jeffersonville, IN
That's the driving distance. It would take 5 hours 35 mins to go from Chattanooga, Tennessee to Jeffersonville, Indiana.
The flight distance (direct flight from Chattanooga, TN to Jeffersonville, IN) is 224.56 mi.
279 mi = 449.41 kms