There are
442 mi
from Chattanooga, TN to Edwardsville, IL
That's the driving distance. It would take 8 hours 14 mins to go from Chattanooga, Tennessee to Edwardsville, Illinois.
The flight distance (direct flight from Chattanooga, TN to Edwardsville, IL) is 365.24 mi.
442 mi = 710.72 kms