There are
353 mi
from Chattanooga, TN to Clarksdale, MS
That's the driving distance. It would take 7 hours 9 mins to go from Chattanooga, Tennessee to Clarksdale, Mississippi.
The flight distance (direct flight from Chattanooga, TN to Clarksdale, MS) is 304.75 mi.
353 mi = 567.57 kms