There are
2,552 mi
from Charlottesville, VA to Santee, CA
That's the driving distance. It would take 1 day 20 hours to go from Charlottesville, Virginia to Santee, California.
The flight distance (direct flight from Charlottesville, VA to Santee, CA) is 2,180.96 mi.
2,552 mi = 4,107.23 kms