Miles between Charleston, SC and Sikeston, MO

There are
749 mi
from Charleston, SC to Sikeston, MO

That's the driving distance. It would take 14 hours 6 mins to go from Charleston, South Carolina to Sikeston, Missouri.

The flight distance (direct flight from Charleston, SC to Sikeston, MO) is 616.20 mi.

749 mi = 1,205.44 kms