Miles between Charleston, SC and Picayune, MS

There are
739 mi
from Charleston, SC to Picayune, MS

That's the driving distance. It would take 13 hours 47 mins to go from Charleston, South Carolina to Picayune, Mississippi.

The flight distance (direct flight from Charleston, SC to Picayune, MS) is 593.84 mi.

739 mi = 1,189.50 kms