Miles between Charleston, SC and Knoxville, TN

There are
373 mi
from Charleston, SC to Knoxville, TN

That's the driving distance. It would take 7 hours 8 mins to go from Charleston, South Carolina to Knoxville, Tennessee.

The flight distance (direct flight from Charleston, SC to Knoxville, TN) is 316.44 mi.

373 mi = 599.93 kms