Miles between Charleston, SC and Gainesville, FL

There are
308 mi
from Charleston, SC to Gainesville, FL

That's the driving distance. It would take 6 hours 8 mins to go from Charleston, South Carolina to Gainesville, Florida.

The flight distance (direct flight from Charleston, SC to Gainesville, FL) is 258.11 mi.

308 mi = 495.76 kms