There are
552 mi
from Champaign, IL to South Sioux City, NE
That's the driving distance. It would take 10 hours 3 mins to go from Champaign, Illinois to South Sioux City, Nebraska.
The flight distance (direct flight from Champaign, IL to South Sioux City, NE) is 453.85 mi.
552 mi = 887.66 kms