There are
2,043 mi
from Centennial, CO to Barnstable, MA
That's the driving distance. It would take 1 day 13 hours to go from Centennial, Colorado to Barnstable, Massachusetts.
The flight distance (direct flight from Centennial, CO to Barnstable, MA) is 1,806.55 mi.
2,043 mi = 3.22 kms