There are
384 mi
from Cedar Rapids, IA to Cape Girardeau, MO
That's the driving distance. It would take 7 hours 29 mins to go from Cedar Rapids, Iowa to Cape Girardeau, Missouri.
The flight distance (direct flight from Cedar Rapids, IA to Cape Girardeau, MO) is 342.39 mi.
384 mi = 618.55 kms