There are
2,833 mi
from Cary, NC to San Mateo, CA
That's the driving distance. It would take 2 days 2 hours to go from Cary, North Carolina to San Mateo, California.
The flight distance (direct flight from Cary, NC to San Mateo, CA) is 2,394.40 mi.
2,833 mi = 3.22 kms