There are
852 mi
from Bethlehem, PA to Edwardsville, IL
That's the driving distance. It would take 16 hours 22 mins to go from Bethlehem, Pennsylvania to Edwardsville, Illinois.
The flight distance (direct flight from Bethlehem, PA to Edwardsville, IL) is 784.14 mi.
852 mi = 1,371.56 kms