There are
1,731 mi
from Barstow, CA to Sikeston, MO
That's the driving distance. It would take 1 day 6 hours to go from Barstow, California to Sikeston, Missouri.
The flight distance (direct flight from Barstow, CA to Sikeston, MO) is 1,536.23 mi.
1,731 mi = 2,785.30 kms