There are
1,765 mi
from Barstow, CA to Cape Girardeau, MO
That's the driving distance. It would take 1 day 6 hours to go from Barstow, California to Cape Girardeau, Missouri.
The flight distance (direct flight from Barstow, CA to Cape Girardeau, MO) is 1,538.70 mi.
1,765 mi = 2,840.18 kms