There are
1,310 mi
from Appleton, WI to Zephyrhills, FL
That's the driving distance. It would take 1 day to go from Appleton, Wisconsin to Zephyrhills, Florida.
The flight distance (direct flight from Appleton, WI to Zephyrhills, FL) is 1,159.74 mi.
1,310 mi = 1.61 kms