There are
661 mi
from Appleton, WI to Wilkinsburg, PA
That's the driving distance. It would take 12 hours 27 mins to go from Appleton, Wisconsin to Wilkinsburg, Pennsylvania.
The flight distance (direct flight from Appleton, WI to Wilkinsburg, PA) is 509.04 mi.
661 mi = 1,063.02 kms