There are
195 mi
from Appleton, WI to Sycamore, IL
That's the driving distance. It would take 3 hours 55 mins to go from Appleton, Wisconsin to Sycamore, Illinois.
The flight distance (direct flight from Appleton, WI to Sycamore, IL) is 157.64 mi.
195 mi = 314.22 kms